Annual report pursuant to Section 13 and 15(d)

STOCK-BASED COMPENSATION (Details 3)

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STOCK-BASED COMPENSATION (Details 3) - USD ($)
 12 Months Ended
Dec. 31, 2017
Dec. 31, 2016
Number of Shares or Options Granted 214,915 802,122
Stock-Based Compensation Expense $ 3,725,792 $ 5,382,060
Stock Option [Member]    
Number of Shares or Options Granted 731,065 446,667
Stock-Based Compensation Expense $ 692,971 $ 190,355
Employees (Common Stock) [Member]    
Number of Shares or Options Granted 158,867
Stock-Based Compensation Expense $ 490,880  
Employees (Series B Preferred Stock) [Member]    
Number of Shares or Options Granted 40,000 430,113
Stock-Based Compensation Expense $ 1,035,406 $ 2,451,220
Directors (Common Stock) [Member]    
Number of Shares or Options Granted 81,061 71,381
Stock-Based Compensation Expense $ 221,973 $ 334,424
Non-Employee Consultants (Common Stock) [Member]    
Number of Shares or Options Granted 389,374 422,971
Stock-Based Compensation Expense $ 1,284,562 $ 2,406,061